Massachusetts General Hospital Department of Psychiatry and Harvard Medical School, Boston, MA 02114, USA.
Psychosomatics. 2011 May-Jun;52(3):245-54. doi: 10.1016/j.psym.2010.12.015.
Body dysmorphic disorder (BDD) is a chronic mental illness characterized by low quality of life and functional disability across multiple domains. Despite the clinical importance of understanding impairment in BDD, there has been little research examining the factors that contribute to these constructs. The present study was designed to examine sociodemographic and clinical correlates of quality of life and disability (work, social, and family) in a sample of individuals with moderately severe BDD symptoms.
Participants completed an internet survey with questions about demographics, BDD phenomenology, treatment, and impairment. Only participants who completed all study measures and received a score≥16 on the 10-item Yale-Brown Obsessive Compulsive Scale, Modified for BDD (BDD-YBOCS), indicating the presence of clinical BDD symptoms, were included in the analysis (n=256). Multivariate regression with backwards variable selection was used to identify significant predictors of quality of life and functional disability, assessed with the Quality of Life Enjoyment and Satisfaction Scale-Short Form (QLESQ-SF) and the Sheehan Disability Scale (SDS), respectively.
BDD symptom severity was inversely associated with quality of life and directly associated with disability in all domains. After controlling statistically for BDD symptom severity, sociodemographic and clinical factors such as age, gender, ethnicity, marital status, insurance, body parts of concern, depression symptoms, and anxiety symptoms were significantly associated with impairment.
Results suggest a multidimensional nature of quality of life and functional disability and underscore the importance of developing holistic treatment strategies to address impairment in BDD.
躯体变形障碍（BDD）是一种慢性精神疾病，其特征是生活质量低，多个领域的功能障碍。尽管了解 BDD 损伤的临床重要性，但很少有研究探讨导致这些结构的因素。本研究旨在检查具有中度严重 BDD 症状的个体样本中的生活质量和残疾（工作、社交和家庭）的社会人口统计学和临床相关性。
参与者完成了一项互联网调查，其中包括有关人口统计学、BDD 现象学、治疗和损伤的问题。只有完成所有研究措施并在 10 项耶鲁-布朗强迫量表（BDD-YBOCS）上得分≥16 的参与者，表明存在临床 BDD 症状，才被纳入分析（n=256）。使用向后变量选择的多元回归来确定生活质量和功能残疾的显著预测因素，分别使用生活质量享受和满意度量表-短格式（QLESQ-SF）和 Sheehan 残疾量表（SDS）进行评估。
BDD 症状严重程度与生活质量呈负相关，与所有领域的残疾呈正相关。在统计学上控制 BDD 症状严重程度后，年龄、性别、种族、婚姻状况、保险、关注的身体部位、抑郁症状和焦虑症状等社会人口统计学和临床因素与损伤显著相关。
结果表明生活质量和功能残疾具有多维性，并强调了制定整体治疗策略来解决 BDD 损伤的重要性。
