Suppr超能文献

管理痛风患者:治疗选择综述。

Managing your patient with gout: a review of treatment options.

机构信息

PMSI Comprehensive Healthcare, Collegeville Family Practice, Collegeville, PA, USA.

出版信息

Postgrad Med. 2011 May;123(3):56-71. doi: 10.3810/pgm.2011.05.2284.

Abstract

Gout is an inflammatory arthritis that typically presents as acute onset, recurrent, monoarticular pain. In most patients, management of pain, risk assessment for future flares, and disability is not optimal and diagnostic and management approaches are applied inconsistently. Obtaining an accurate patient history, including comorbidities, concomitant medications, and familial history, is important for optimal results. Recognizing the acute flare in the patient at risk and establishing a definitive diagnosis of gout should be conducted promptly. Therapeutic options appropriate for treating the acute flare include colchicine, nonsteroidal anti-inflammatory drugs, and corticosteroids. After flare remission, prophylaxis with a flare prevention medication, such as colchicine, should be administered followed by initiation of urate-lowering therapy with allopurinol or febuxostat. Patient education, especially counseling on risk factors and contributors to hyperuricemia and gout, can improve the likelihood of successful therapy for this often suboptimally managed disease.

摘要

痛风是一种炎症性关节炎,通常表现为急性发作、反复发作、单关节炎疼痛。在大多数患者中,疼痛的管理、未来发作的风险评估和残疾的管理并不理想,诊断和管理方法的应用也不一致。获得准确的患者病史,包括合并症、伴随药物和家族史,对于获得最佳结果非常重要。及时识别处于危险中的患者的急性发作并确立痛风的明确诊断至关重要。适用于治疗急性发作的治疗选择包括秋水仙碱、非甾体抗炎药和皮质类固醇。急性发作缓解后,应给予预防性药物(如秋水仙碱)预防发作,然后开始使用别嘌醇或非布司他进行降尿酸治疗。患者教育,特别是对高尿酸血症和痛风的风险因素和促成因素的咨询,可以提高对这种经常管理不佳的疾病进行成功治疗的可能性。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验