Le Gal F-A, Toutous-Trellu L, Kaya G, Salomon D
Clinique de dermatologie HUG, 1211 Geneve.
Rev Med Suisse. 2011 Apr 6;7(289):765-6, 768-71.
Lentigo maligna (LM) and lentigo maligna melanoma (LMM) account for about 10% of all melanomas. They have distinct clinical and histological features as well as specific epidemiology, natural history, evolution, and genetics. Epidemiology of these tumors progressively concerns younger patients. Diagnostic and preparation of surgical removal of LM and LMM can now be optimized by new technologies of imaging, like dermoscopy or in vivo confocal reflectance microscopy. Surgery is the treatment of choice, but alternative options can be considered, especially for the elderly for whom the needs for efficiency and acceptability should be met.
恶性雀斑样痣（LM）和恶性雀斑样痣黑色素瘤（LMM）约占所有黑色素瘤的10%。它们具有独特的临床和组织学特征，以及特定的流行病学、自然史、演变过程和遗传学特征。这些肿瘤的流行病学越来越多地涉及年轻患者。如今，像皮肤镜检查或体内共聚焦反射显微镜等新的成像技术可以优化LM和LMM的诊断及手术切除准备工作。手术是首选的治疗方法，但也可以考虑其他替代方案，特别是对于老年患者，应满足其对治疗效率和可接受性的需求。
