Tianjin Women's and Children's Health Center, Tianjin, China.
Diabet Med. 2011 Jun;28(6):652-7. doi: 10.1111/j.1464-5491.2010.03205.x.
To investigate the trend in the prevalence of gestational diabetes mellitus during 1999-2008 in women living in urban Tianjin, China.
A universal screening for gestational diabetes mellitus has become an integral part of the antenatal care in Tianjin, China from 1998. A total of 105,473 pregnant women living in the six urban districts of Tianjin, China, participated in the gestational diabetes mellitus screening programme between December 1998 and December 2008. The screening test consisted of a 50-g 1-h glucose test. Women who had a glucose reading ≥7.8 mmol/l at the initial screening were invited to undergo the standard 2-h oral glucose tolerance test with a 75-g glucose load. Gestational diabetes mellitus was confirmed using the World Health Organization's diagnostic criteria.
The adjusted prevalence of gestational diabetes mellitus increased by 2.8 times during 1999-2008, from 2.4 to 6.8% (P<0.0001 for linear trend). In 2008, the age-specific prevalence of gestational diabetes mellitus was the highest among women aged 30-34 years (11.3%) and lowest among women aged 25 and under (1.2%). In women aged 35 years and more, the prevalence was 5.3%.
The prevalence of gestational diabetes mellitus has markedly been increasing in a universally screened urban Chinese female population and has become an important public health problem in China.
调查 1999 年至 2008 年期间中国天津市城区女性中妊娠期糖尿病患病率的变化趋势。
从 1998 年开始,中国天津市的产前保健中普遍开展了妊娠期糖尿病筛查。共有 105473 名居住在中国天津市六个城区的孕妇参加了 1998 年 12 月至 2008 年 12 月的妊娠期糖尿病筛查计划。筛查试验包括 50g 1 小时葡萄糖检测。初始筛查葡萄糖读数≥7.8mmol/L 的妇女被邀请进行标准的 2 小时口服葡萄糖耐量试验,负荷 75g 葡萄糖。采用世界卫生组织的诊断标准确诊妊娠期糖尿病。
1999 年至 2008 年间,妊娠期糖尿病的调整患病率增加了 2.8 倍,从 2.4%升至 6.8%(线性趋势 P<0.0001)。2008 年,年龄别妊娠期糖尿病患病率在 30-34 岁的妇女中最高(11.3%),在 25 岁及以下的妇女中最低(1.2%)。在 35 岁及以上的妇女中,患病率为 5.3%。
在中国普遍筛查的城市女性人群中,妊娠期糖尿病的患病率显著增加,已成为中国一个重要的公共卫生问题。