Division, of Rehabilitation Sciences, University of Texas Medical Branch, 301 University Blvd. Galveston, TX 77555-1137, USA.
Arch Gerontol Geriatr. 2012 Jan-Feb;54(1):202-5. doi: 10.1016/j.archger.2011.04.001. Epub 2011 May 12.
Depression is often associated with illness or injury requiring acute hospitalization, particularly in older adults. We sought to determine patterns of change in depressive symptoms in older adults from hospitalization to 3 months post discharge and to examine factors associated with depressive symptoms 3 months after discharge. The study included 197 patients aged 65 years or older hospitalized with an acute medical illness. Sociodemographic and clinical measures, including depressive symptoms using the Center for Epidemiologic Study-Depression (CES-D) scale, were collected during the inpatient stay and at 3 months post discharge. Mean age was 75.3 ± 7.5 (± S.D.) years, 59% of the participants were female, 61% unmarried, and 72% had a high school education or more. High depressive symptoms (i.e., CES-D ≥ 16) were reported in 37% at admission. Of the 8% depressed at follow-up, 81% were also depressed at admission; 19% were new cases of depression. Depressive symptoms 3 months post-hospitalization were significantly associated with follow-up daily living skills (p=0.001) and social support (p<0.0001). Patients with persistent depressive symptoms make up the majority of post-hospitalization depression cases. Post-hospitalization social support and daily living skills appear to be important in the management of follow-up depressive symptoms.
抑郁症常与需要急性住院治疗的疾病或损伤相关，尤其是在老年人中。我们旨在确定老年人从住院到出院后 3 个月期间抑郁症状的变化模式，并探讨与出院后 3 个月时抑郁症状相关的因素。该研究纳入了 197 名年龄在 65 岁及以上、因急性内科疾病住院的患者。在住院期间和出院后 3 个月收集了社会人口统计学和临床指标，包括使用流行病学研究中心抑郁量表（CES-D）评估的抑郁症状。平均年龄为 75.3±7.5（±标准差）岁，59%的参与者为女性，61%未婚，72%具有高中及以上学历。入院时报告有 37%存在较高的抑郁症状（即 CES-D≥16）。在随访时 8%为抑郁患者，其中 81%在入院时也存在抑郁；19%为新发生的抑郁病例。出院后 3 个月的抑郁症状与随访时的日常生活技能（p=0.001）和社会支持（p<0.0001）显著相关。持续性抑郁症状的患者占出院后抑郁病例的大多数。出院后的社会支持和日常生活技能似乎对管理随访时的抑郁症状很重要。
