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抑郁症是否能预测老年内科住院患者的不良结局?一项针对筛选进入试验的个体的前瞻性队列研究。

Does depression predict adverse outcomes for older medical inpatients? A prospective cohort study of individuals screened for a trial.

作者信息

Cullum Sarah, Metcalfe Chris, Todd Chris, Brayne Carol

机构信息

West Suffolk Hospital and Department of Public Health and Primary Care, University of Cambridge, UK.

出版信息

Age Ageing. 2008 Nov;37(6):690-5. doi: 10.1093/ageing/afn193.

DOI:10.1093/ageing/afn193
PMID:19004962
Abstract

OBJECTIVE

to examine the relationship between depressive symptoms and hospital outcomes in an unselected consecutive sample of older medical inpatients.

DESIGN

a prospective cohort study of individuals screened for a trial.

SETTING

medical wards of UK district general hospital in rural East Anglia.

PARTICIPANTS

six hundred and seventeen medical inpatients aged 65+ were randomly selected from consecutive admissions. Baseline measures: 15-item Geriatric Depression Scale (GDS-15), the Abbreviated Mental Test Score (AMTS) and the Cumulative Illness Rating Scale-Geriatric (CIRS-G).

MAIN OUTCOME MEASURES

length of hospital stay; discharge to a community hospital (for rehabilitation), institutional care or usual place of residence; dying in hospital.

RESULTS

depressive symptoms are independently associated with an increased likelihood of inpatient death and transfer to a community hospital for rehabilitation, but are not associated with longer length of stay.

CONCLUSIONS

research evaluating effectiveness of identification and treatment of depression in older medical inpatients should consider including inpatient death and use of rehabilitation services as potential outcomes.

摘要

目的

在未经过挑选的连续入住的老年内科住院患者样本中,研究抑郁症状与住院结局之间的关系。

设计

对筛选进入一项试验的个体进行前瞻性队列研究。

地点

东安格利亚农村地区英国区级综合医院的内科病房。

参与者

从连续入院患者中随机选取617名65岁及以上的内科住院患者。基线测量:15项老年抑郁量表(GDS - 15)、简易精神状态检查表(AMTS)和累积疾病评定量表 - 老年版(CIRS - G)。

主要结局指标

住院时间;出院后转至社区医院(进行康复治疗)、机构护理或常住地;在医院死亡。

结果

抑郁症状与住院患者死亡及转至社区医院进行康复治疗的可能性增加独立相关,但与住院时间延长无关。

结论

评估老年内科住院患者抑郁识别和治疗效果的研究应考虑将住院患者死亡及康复服务的使用作为潜在结局。

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