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先心病手术治疗后院内死亡率与手术量对死亡率的影响。

Impact of prior hospital mortality versus surgical volume on mortality following surgery for congenital heart disease.

机构信息

Children's Healthcare of Atlanta, Emory University, Sibley Heart Center, Atlanta, GA, USA.

出版信息

J Thorac Cardiovasc Surg. 2011 Oct;142(4):882-6. doi: 10.1016/j.jtcvs.2011.04.011. Epub 2011 May 14.

Abstract

OBJECTIVE

Our objective was to assess the relationships of a hospital's past adjusted in-hospital mortality and surgical volume with future in-hospital mortality after surgery for congenital heart disease.

METHODS

Using the Pediatric Health Information Systems database, we (1) calculated hospital surgical volume and standardized mortality ratio (= observed number of deaths/expected number of deaths adjusted for surgery type) for January 2004 through June 2006 for children (0-18 years) after surgery for congenital heart disease at 38 hospitals and (2) assessed the relationship between these values and subsequent mortality during July 2006 through December 2008. We constructed Poisson regression models to estimate risk of mortality, adjusting for age, race, sex, genetic syndrome, insurance type, and surgery type (using the Risk Adjustment in Congenital Heart Surgery method).

RESULTS

There were 49,792 hospital encounters during 2004 through 2008 for pediatric patients having surgery for congenital heart disease, with an overall in-hospital mortality of 3.45%. For the 24,112 eligible encounters during July 2006 through December 2008, a hospital's prior standardized mortality ratio was significantly associated with postoperative in-hospital mortality (P < .0001), and a hospital's prior surgical volume had only borderline significance (P = .0792). On stratified analysis, past standardized mortality ratio was associated with mortality for both lower- and higher-risk surgical risk categories (P = .0105 and .0015, respectively). Hospital surgical volume was not significantly associated with mortality for lower-risk categories (P = .4122), but it was borderline significant for higher-risk categories (P = .0678).

CONCLUSIONS

In this data set, prior hospital surgical volume tended to be associated with improved mortality after higher-risk operations in pediatric patients with congenital heart disease, whereas prior hospital postoperative mortality was significantly associated with mortality across all risk strata of congenital heart surgery.

摘要

目的

评估医院既往调整后院内死亡率和手术量与先心病手术后未来院内死亡率之间的关系。

方法

利用儿科健康信息系统数据库,我们(1)计算了 2004 年 1 月至 2006 年 6 月间 38 家医院接受先心病手术后 0-18 岁儿童的医院手术量和标准化死亡率(=观察到的死亡人数/手术类型调整后的预期死亡人数);(2)评估了这些值与 2006 年 7 月至 2008 年 12 月期间随后死亡率之间的关系。我们构建泊松回归模型来估计死亡率风险,调整因素包括年龄、种族、性别、遗传综合征、保险类型和手术类型(使用先天性心脏病手术风险调整方法)。

结果

2004 年至 2008 年期间,共有 49792 例儿科患者接受先心病手术,院内总体死亡率为 3.45%。对于 2006 年 7 月至 2008 年 12 月期间的 24112 例合格手术,医院既往标准化死亡率与术后院内死亡率显著相关(P<.0001),医院既往手术量仅具有边缘显著性(P=.0792)。分层分析显示,过去的标准化死亡率与低风险和高风险手术风险类别死亡率均相关(P=.0105 和.0015)。医院手术量与低风险类别死亡率无显著相关性(P=.4122),但与高风险类别死亡率具有边缘相关性(P=.0678)。

结论

在这个数据集里,既往医院手术量与先心病高风险手术的患儿术后死亡率的改善趋势相关,而既往医院术后死亡率与所有先天性心脏病手术风险分层的死亡率显著相关。

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