Center for Neurological Restoration, Department of Neurosurgery, Cleveland Clinic Foundation, 9500 Euclid Avenue, S31, Cleveland, Ohio 44195, USA.
J Clin Neurosci. 2011 Jul;18(7):910-5. doi: 10.1016/j.jocn.2010.11.020. Epub 2011 May 14.
Post-operative edema around a deep brain stimulation (DBS) lead is a rare presentation. Post-operative edema that is symptomatic, self-limiting and not due to infection, in particular, is rarely reported as a separate entity. We aim to discuss the morphological characteristics of post-operative edema around a DBS lead with an insight into possible etiologies and management. We present eight patients with symptomatic, self-limiting peri-electrode edema post-DBS electrode implantation who presented post-operatively with distinct clinical presentations with imaging that revealed a hypodense area in the white matter surrounding the DBS electrode. Local and systemic tests for infection were negative. The edema resolved over time without surgical intervention. The etiology of the edema remains obscure. The transient nature of the edema and benign course with rapid and full resolution in all our patients cautions against any hasty decision to explant the electrode, in the absence of any obvious signs of infection.
脑深部电刺激(DBS)术后导丝周围水肿是一种罕见的表现。术后出现有症状、自限性、非感染性水肿的情况尤其少见,很少被作为一个单独的实体来报道。我们旨在讨论 DBS 术后导丝周围水肿的形态学特征,并深入探讨其可能的病因和处理方法。我们报告了 8 例 DBS 术后电极植入后出现症状性、自限性的电极周围水肿的患者,这些患者术后出现了不同的临床表现,影像学显示 DBS 电极周围的白质中有一个低密区。局部和全身感染检查均为阴性。水肿随时间推移逐渐消退,无需手术干预。水肿的病因仍不清楚。所有患者的水肿均为一过性,且具有良性病程,在所有患者中均迅速完全消退,这提示在没有明显感染迹象的情况下,不应匆忙决定将电极取出。