Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Alice, South Africa.
Int J Environ Health Res. 2011 Dec;21(6):402-14. doi: 10.1080/09603123.2011.572278. Epub 2011 May 23.
We assessed the antibiogram characteristics of some Vibrio species isolated from wastewater final effluents in a typical peri-urban community of South Africa. Marked resistances were noted against erythromycin (100%), chloramphenicol (100%), nitrofurantoin, cefuroxime and cephalothin (90-95%) in V. parahaemolyticus, V. fluvialis and V. vulnificus, respectively. Fourteen antibiotypes were identified, with multiresistance to 8-10 antibiotics being common. The antibiotypes AMP, PEN, STR, SUL, TMP, COT, CHL, ERY, CIP and PB demonstrated by V. fluvialis were the most prevalent (17.24%). Eight putative antibiotic resistance genes were identified with floR being the mostly (100%) detected in all the three species while tet(A) was the least with 65% prevalence in V. vulnificus, 7.14% in V. parahaemolyticus and none in V. fluvialis. These results demonstrate that the treated effluent system are reservoirs for various antibiotic resistance genes which could be disseminated to inhabitants downstream the plant and pose health risk to the communities who are dependent upon the watershed for domestic and recreational purposes.
我们评估了南非一个典型城郊社区废水中某些弧菌属物种的抗生素耐药谱特征。副溶血弧菌、河弧菌和创伤弧菌对红霉素（100%）、氯霉素（100%）、呋喃妥因、头孢呋辛和头孢噻吩的耐药性显著，耐药率分别为 90-95%。共鉴定出 14 种抗生素耐药型，对 8-10 种抗生素的多重耐药较为常见。河弧菌表现出的 AMP、PEN、STR、SUL、TMP、COT、CHL、ERY、CIP 和 PB 抗生素耐药型最为普遍（17.24%）。共鉴定出 8 种潜在的抗生素耐药基因，其中 floR 在所有三种弧菌中均被检测到（100%），tet(A) 的检出率最低，在创伤弧菌中为 65%，在副溶血弧菌中为 7.14%，在河弧菌中则未检出。这些结果表明，处理后的污水系统是各种抗生素耐药基因的储存库，这些基因可能会传播到工厂下游的居民中，并对依赖流域进行家庭和娱乐活动的社区构成健康风险。
