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[格但斯克医科大学耳鼻喉科材料中的中耳非嗜铬性副神经节瘤(化学感受器瘤)]

[Nonchromaffin paragangliomas (chemodectoma) of the middle ear in the material of the ENT Department Medical University of Gdańsk].

作者信息

Kuczkowski Jerzy, Przewoźny Tomasz, Biernat Wojciech, Dubaniewicz-Wybieralska Mirosława

机构信息

Katedra i Klinika Otolaryngologii GUMed, Gdańsk.

出版信息

Otolaryngol Pol. 2011 Jan-Feb;65(1):40-6. doi: 10.1016/S0030-6657(11)70626-6.

Abstract

INTRODUCTION

Nonchromaffin paraganglioma (chemodectoma) is the most common neoplasm of the middle ear. The diagnosis and treatment is one of the most challenging in otolaryngology.

THE AIM OF THE STUDY

was clinical and epidemiological analysis of patients with nonchromaffin paraganglioma of the middle ear.

MATERIAL AND METHODS

The material consisted of 13 patients (10 females, 3 males), age 19-62 years, treated for paraganglioma of the middle ear in the ENT Department Medical University of Gdańsk between 1968 and 2009. We analyzed the symptoms and results of additional diagnostic tests necessary to establish the diagnosis.

RESULTS

We have diagnosed 12 cases of benign chemodectoma (92.3%) and 1 case of chemodectoma malignum (7.7%). The surgical treatment was applied in 6 patients (46.1%), 4 patients (30.8%) received complementary radiotherapy and 3 patients (23.1%) were treated only with radiotherapy.

CONCLUSIONS

The diagnosis of paragangliomas of the ear is difficult and should be based on clinical data, audiometric tests, CT, MRI and histological examination. Surgical treatment of paragangliomas is limited to early stages of the disease. The results of the research show that the best therapeutic method in advanced cases is surgical treatment with complementary radiotherapy.

摘要

引言

非嗜铬性副神经节瘤(化学感受器瘤)是中耳最常见的肿瘤。其诊断和治疗是耳鼻咽喉科最具挑战性的问题之一。

研究目的

对中耳非嗜铬性副神经节瘤患者进行临床和流行病学分析。

材料与方法

材料包括1968年至2009年期间在格但斯克医科大学耳鼻喉科接受中耳副神经节瘤治疗的13例患者(10例女性,3例男性),年龄19 - 62岁。我们分析了确诊所需的症状和其他诊断检查结果。

结果

我们诊断出12例良性化学感受器瘤(92.3%)和1例恶性化学感受器瘤(7.7%)。6例患者(46.1%)接受了手术治疗,4例患者(30.8%)接受了辅助放疗,3例患者(23.1%)仅接受了放疗。

结论

耳部副神经节瘤的诊断困难,应基于临床资料、听力测试、CT、MRI和组织学检查。副神经节瘤的手术治疗仅限于疾病的早期阶段。研究结果表明,晚期病例的最佳治疗方法是手术治疗加辅助放疗。

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