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良性前列腺增生症症状性经尿道 GreenLight HPS™ 激光前列腺汽化切除术的中期疗效。

Intermediate outcomes of GreenLight HPS™ laser photoselective vaporization prostatectomy for symptomatic benign prostatic hyperplasia.

机构信息

Department of Urology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

出版信息

J Endourol. 2011 Jun;25(6):1037-41. doi: 10.1089/end.2010.0512. Epub 2011 May 16.

DOI:10.1089/end.2010.0512
PMID:21574860
Abstract

PURPOSE

GreenLight HPS™ laser photoselective vaporization prostatectomy (PVP) is a treatment option for lower urinary tract symptoms secondary to benign prostatic hyperplasia. We review our experience using the 120 W GreenLight HPS laser system.

MATERIALS AND METHODS

We prospectively evaluated our experience with GreenLight HPS laser PVP. All patients who failed medical therapy underwent GreenLight HPS laser PVP (C.W.). All had American Urological Association Symptom Score, Quality of Life score, Sexual Health Inventory for Men, American Society of Anesthesiologists risk score, serum prostate-specific antigen, maximum flow rate, and postvoid residual determinations and volumetric measurements with transrectal ultrasonography. Transurethral PVP was performed using a GreenLight HPS side-firing laser system.

RESULTS

170 consecutive patients were identified, having a mean age of 67.4±9.5 years. The mean prostate volume was 65.3±36.7  mL and mean American Society of Anesthesiologists score was 2.3±0.7. Mean laser time, operating time, and energy usage were 14.1±10.5 minutes, 33.5±24.7 minutes, and 95.0±72.3  kJ, respectively. All were outpatient procedures with 100 (58.8%) patients catheter-free at discharge. 35 (20.5%) and 26 (15.3%) patients had follow-up of 24 and 36 months, respectively. Eight (4.7%) patients developed a urinary tract infection. No bladder neck contracture or urethral stricture were reported. American Urological Association Symptom Score, Quality of Life, maximum flow rate, and postvoid residual showed immediate and stable improvement from baseline (p<0.05) that has been durable to 36 months. The Sexual Health Inventory for Men score did not change postoperatively.

CONCLUSIONS

Our intermediate results suggest that GreenLight HPS laser PVP is safe, effective, and durable for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia.

摘要

目的

绿光 HPS™激光前列腺光汽化切除术(PVP)是治疗良性前列腺增生引起下尿路症状的一种选择。我们回顾了使用 120W 绿光 HPS 激光系统的经验。

材料与方法

我们前瞻性地评估了使用绿光 HPS 激光 PVP 的经验。所有药物治疗失败的患者均接受绿光 HPS 激光 PVP(C.W.)治疗。所有患者均进行美国泌尿外科学会症状评分、生活质量评分、男性性功能健康问卷、美国麻醉医师协会风险评分、血清前列腺特异性抗原、最大尿流率、残余尿量测定和经直肠超声体积测量。经尿道 PVP 采用绿光 HPS 侧射激光系统进行。

结果

共确定 170 例连续患者,平均年龄 67.4±9.5 岁。前列腺平均体积为 65.3±36.7ml,平均美国麻醉医师协会评分为 2.3±0.7。平均激光时间、手术时间和能量使用分别为 14.1±10.5 分钟、33.5±24.7 分钟和 95.0±72.3kJ。所有患者均为门诊手术,出院时 100 例(58.8%)患者无需导尿。分别有 35 例(20.5%)和 26 例(15.3%)患者获得 24 个月和 36 个月的随访。8 例(4.7%)患者发生尿路感染。无膀胱颈挛缩或尿道狭窄报告。美国泌尿外科学会症状评分、生活质量评分、最大尿流率和残余尿量自基线开始即有明显且稳定的改善(p<0.05),且在 36 个月时仍保持稳定。男性性功能健康问卷评分术后无变化。

结论

我们的中期结果表明,绿光 HPS 激光 PVP 治疗良性前列腺增生引起的下尿路症状安全、有效且持久。

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引用本文的文献

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Risk Factors for Failure of Early Catheter Removal After Greenlight HPS Laser Photoselective Vaporization Prostatectomy in Men With Benign Prostatic Hyperplasia.良性前列腺增生男性患者接受绿激光前列腺汽化术(HPS)后早期拔除导尿管失败的危险因素
Korean J Urol. 2013 Jan;54(1):31-5. doi: 10.4111/kju.2013.54.1.31. Epub 2013 Jan 18.
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Does prostate configuration affect the efficacy and safety of GreenLight HPS™ laser photoselective vaporization prostatectomy (PVP)?前列腺形态是否会影响 GreenLight HPS™ 激光前列腺选择性汽化术(PVP)的疗效和安全性?
Lasers Med Sci. 2013 Feb;28(2):473-8. doi: 10.1007/s10103-012-1085-4. Epub 2012 Mar 30.