Department of Psychiatry and Psychotherapy, University Medical Centre, Mainz, Germany.
Arch Clin Neuropsychol. 2011 Jun;26(4):314-21. doi: 10.1093/arclin/acr024. Epub 2011 May 15.
The majority of patients with Major Depressive Disorder (MDD) suffer from significant executive dysfunctions. To investigate the time course of executive functions during antidepressant treatment, repeated measures of executive functions are necessary. In order to avoid practice effects, the assessment of alternate forms is suggested. The aim of this study was to compare the processing times of four alternate versions of the Trail Making Test (TMT) A and B in patients with MDD. Fifty-five subjects with DSM-IV MDD were included in the study. We analyzed mean processing times and retest reliability of the four versions of TMT A and B. Mean processing times did not differ between the four tested versions of TMT A and B. Retest reliability of TMT A and B was between 0.76 and 0.89 and between 0.86 and 0.94, respectively. Because of their identical difficulty and high reliability, the herein described versions of the TMT A and B are suitable for sequential testing of executive functioning.
大多数重度抑郁症（MDD）患者都存在明显的执行功能障碍。为了研究抗抑郁治疗过程中执行功能的时间进程，有必要对执行功能进行重复测量。为了避免练习效应，建议评估交替形式。本研究的目的是比较四种交替形式的连线测试（TMT）A 和 B 在 MDD 患者中的处理时间。该研究纳入了 55 名符合 DSM-IV MDD 标准的受试者。我们分析了 TMT A 和 B 的四个版本的平均处理时间和重测信度。TMT A 和 B 的四个测试版本之间的平均处理时间没有差异。TMT A 和 B 的重测信度分别在 0.76 和 0.89 之间，以及在 0.86 和 0.94 之间。由于它们具有相同的难度和高可靠性，因此在此描述的 TMT A 和 B 的版本适合执行功能的顺序测试。
