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4-[(2-羟基-1-萘基)(哌啶-1-基)甲基]苯甲腈

4-[(2-Hydr-oxy-1-naphth-yl)(piperidin-1-yl)meth-yl]benzonitrile.

作者信息

Zhang Yuan, Li Yong Hua

机构信息

Ordered Matter Science Research Center, College of Chemistry and Chemical, Engineering, Southeast UniVersity, Nanjing 211189, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 29;65(Pt 9):o2257. doi: 10.1107/S1600536809033728.

DOI:10.1107/S1600536809033728
PMID:21577653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2970085/
Abstract

In the title compound, C(23)H(22)N(2)O, obtained from the condensation reaction of 4-formyl-benzonitrile, 2-naphthol and piperidine, the dihedral angle between the naphthalene ring system and the benzene ring is 75.31 (4)°. The piperidine ring adopts a chair conformation. The crystal structure is stabilized by inter-molecular C-H⋯N hydrogen bonds, which link the mol-ecules into centrosymmetric dimers. An intra-molecular O-H⋯N hydrogen bond is also present.

摘要

在由4-甲酰基苯甲腈、2-萘酚和哌啶的缩合反应制得的标题化合物C₂₃H₂₂N₂O中，萘环体系与苯环之间的二面角为75.31 (4)°。哌啶环呈椅式构象。晶体结构通过分子间C—H⋯N氢键得以稳定，这些氢键将分子连接成中心对称的二聚体。分子内还存在O—H⋯N氢键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5938/2970085/6604ace01626/e-65-o2257-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5938/2970085/900ad0ec1c5d/e-65-o2257-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5938/2970085/6604ace01626/e-65-o2257-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5938/2970085/900ad0ec1c5d/e-65-o2257-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5938/2970085/6604ace01626/e-65-o2257-fig2.jpg

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