Cree I A, Bingham B J, Ramesar K C
Department of Otolarynology, Ninewells Hospital and Medical School, Dundee, Scotland.
J Laryngol Otol. 1990 Feb;104(2):159-61. doi: 10.1017/s0022215100112162.
A granular cell tumour may present as clinically innocuous lesions on the vocal cords and the diagnosis is usually made by histopathology. However, the granular cells characteristic of this tumour may not be obvious and accompanying epithelial hyperplasia may be interpreted by the pathologist as invasive squamous cell carcinoma. Good communication between pathologist and surgeon is required to ensure that clinically benign lesions on the vocal cords are not misdiagnosed. The diagnosis of granular cell tumour can be confirmed by immunocytochemical staining for S100 antigen.
颗粒细胞瘤可能表现为声带处临床上无害的病变，其诊断通常通过组织病理学做出。然而，该肿瘤特征性的颗粒细胞可能不明显，且伴随的上皮增生可能被病理学家解释为浸润性鳞状细胞癌。病理学家和外科医生之间需要良好的沟通，以确保声带处临床上的良性病变不会被误诊。颗粒细胞瘤的诊断可通过对S100抗原进行免疫细胞化学染色来确认。
