1-[3,5-双（三氟甲基）苯基]-3-[（5-乙烯基-1-氮杂双环[2.2.2]辛-2-基）（6-甲氧基喹啉-4-基）甲基]硫脲-1-脯氨酸-甲醇（1/1/1）
1-[3,5-Bis(trifluoro-meth-yl)phen-yl]-3-[(5-ethenyl-1-aza-bicyclo-[2.2.2]octan-2-yl)(6-methoxy-quinolin-4-yl)meth-yl]thio-urea-l-proline-methanol (1/1/1).
作者信息
Muramulla Savitha, Arman Hadi D, Zhao Cong-Gui, Tiekink Edward R T
出版信息
Acta Crystallogr Sect E Struct Rep Online. 2009 Nov 14;65(Pt 12):o3070. doi: 10.1107/S1600536809047072.
Abstract
In the methanol solvate of the title 1:1 cocrystal, C(29)H(28)F(6)N(4)OS·C(5)H(9)NO(2)·CH(4)O, the l-proline mol-ecule exists as a zwitterion. In the crystal, the disubstituted thio-urea, l-proline and methanol mol-ecules are linked by N-H⋯O and N-H⋯N hydrogen bonds, forming a two-dimensional array in the ab plane.
摘要
在标题为1:1共晶体的甲醇溶剂化物C(29)H(28)F(6)N(4)OS·C(5)H(9)NO(2)·CH(4)O中，L-脯氨酸分子以两性离子形式存在。在晶体中，二取代硫脲、L-脯氨酸和甲醇分子通过N-H⋯O和N-H⋯N氢键相连，在ab平面上形成二维阵列。
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