Suppr超能文献

2,4-Bis(2-fluoro-phen-yl)-1-methyl-3-aza-bicyclo-[3.3.1]nonan-9-one.

作者信息

Parthiban P, Ramkumar V, Jeong Yeon Tae

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 19;66(Pt 1):o194-5. doi: 10.1107/S1600536809053677.

Abstract

The crystal structure of the title compound, C(21)H(21)F(2)NO, shows that the compound exists in a twin-chair conformation with an equatorial orientation of the ortho-fluoro-phenyl groups on either side of the secondary amino group. The title compound is a 1-methyl-ated analog of 2,4-bis-(2-fluoro-phen-yl)-3-aza-bicyclo-[3.3.1]nonan-9-one; the two compound both exhibit the same stereochemistry but the orientation of the ortho-fluoro-phenyl rings differs slightly. In the title compound, the rings are orientated at a dihedral angle of 36.70 (3)° with respect to one another, whereas in the non-methyl analog, the angle is 25.68 (4)°. The crystal structure of the title compound is stabilized by an inter-molecular N-H⋯π inter-action and a weak C-H⋯F inter-action.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6781/2980085/124bd8f0f8bf/e-66-0o194-fig1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验