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2,4-双（2-氟苯基）-3-氮杂双环-[3.3.1]壬烷-9-酮

2,4-Bis(2-fluoro-phen-yl)-3-aza-bicyclo-[3.3.1]nonan-9-one.

作者信息

Parthiban P, Ramkumar V, Jeong Yeon Tae

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 17;65(Pt 7):o1596. doi: 10.1107/S1600536809022065.

DOI:10.1107/S1600536809022065
PMID:21582870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2969275/
Abstract

The title compound, C(20)H(19)F(2)NO, exists in a twin-chair conformation with an equatorial orientation of the two 2-fluoro-phenyl groups on both sides of the secondary amine group. The benzene rings are orientated at an angle of 25.68 (4)° with respect to one another and the F atoms point upwards (towards the carbonyl group). The crystal is stabilized by an inter-molecular N-H⋯π inter-action.

摘要

标题化合物C(20)H(19)F(2)NO以双椅式构象存在，仲胺基团两侧的两个2-氟苯基呈赤道取向。苯环彼此间的夹角为25.68 (4)°，氟原子向上指向（朝向羰基）。该晶体通过分子间N-H⋯π相互作用得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edb4/2969275/931bae699eaf/e-65-o1596-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edb4/2969275/c6034ea0a526/e-65-o1596-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edb4/2969275/931bae699eaf/e-65-o1596-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edb4/2969275/c6034ea0a526/e-65-o1596-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/edb4/2969275/931bae699eaf/e-65-o1596-fig2.jpg

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