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4-[(1,5-二苄基-2,4-二氧代-2,3,4,5-四氢-1H-1,5-苯并二氮杂卓-3-基)甲基]-1-正辛基-1H-1,2,3-三唑

4-[(1,5-Dibenzyl-2,4-dioxo-2,3,4,5-tetra-hydro-1H-1,5-benzodiazepin-3-yl)meth-yl]-1-n-octyl-1H-1,2,3-triazole.

作者信息

Jabli Hind, Ouazzani Chahdi F, Saffon Natalie, Essassi El Mokhtar, Ng Seik Weng

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 24;66(Pt 1):o231. doi: 10.1107/S1600536809054476.

DOI:10.1107/S1600536809054476
PMID:21580113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2980118/
Abstract

The reaction of 1,5-dibenzyl-3-propargyl-1,5-benzodiazepine-2,4-dione with 1-azido-n-octane in the presence of catalysts leads to the formation of the title compound, C(34)H(39)N(5)O(2), which features a phenyl-ene ring fused with a seven-membered diazepinyl ring. The latter ring adopts a boat conformation with the octyltriazolylmethyl-bearing C atom as the prow and the fused-ring C atoms as the stern. The octyltriazolylmethyl substituent occupies an axial position.

摘要

1,5-二苄基-3-炔丙基-1,5-苯并二氮杂䓬-2,4-二酮与1-叠氮基正辛烷在催化剂存在下反应生成标题化合物C(34)H(39)N(5)O(2)，其具有一个与七元二氮杂䓬环稠合的亚苯基环。后一个环呈船式构象，带有辛基三唑基甲基的C原子为船头，稠合环的C原子为船尾。辛基三唑基甲基取代基占据轴向位置。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9b/2980118/9d84d0a1a2e4/e-66-0o231-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9b/2980118/9d84d0a1a2e4/e-66-0o231-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9b/2980118/9d84d0a1a2e4/e-66-0o231-fig1.jpg

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