• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

2-（4-氟苯基）-5-碘-3-甲基亚磺酰基-1-苯并呋喃

2-(4-Fluoro-phen-yl)-5-iodo-3-methyl-sulfinyl-1-benzofuran.

作者信息

Choi Hong Dae, Seo Pil Ja, Son Byeng Wha, Lee Uk

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 4;66(Pt 1):o44. doi: 10.1107/S1600536809051642.

DOI:10.1107/S1600536809051642
PMID:21580148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2980179/
Abstract

In the title compound, C(15)H(10)FIO(2)S, the O atom and the methyl group of the methyl-sulfinyl substituent are located on opposite sides of the plane through the benzofuran fragment. The 4-fluoro-phenyl ring is rotated out of the benzofuran plane by a dihedral angle of 28.33 (5)°. The crystal structure is stabilized by a weak non-classical inter-molecular C-H⋯O hydrogen bond and an I⋯O halogen interaction [3.211 (1) Å].

摘要

在标题化合物C₁₅H₁₀FIO₂S中，甲基亚砜取代基的O原子和甲基位于通过苯并呋喃片段的平面的相对两侧。4-氟苯基环与苯并呋喃平面的二面角为28.33（5）°。晶体结构通过弱的非经典分子间C-H⋯O氢键和I⋯O卤键相互作用[3.211（1）Å]得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9965/2980179/1a3730d1240e/e-66-00o44-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9965/2980179/d5cd2ef59b7f/e-66-00o44-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9965/2980179/1a3730d1240e/e-66-00o44-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9965/2980179/d5cd2ef59b7f/e-66-00o44-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9965/2980179/1a3730d1240e/e-66-00o44-fig2.jpg

相似文献

1
2-(4-Fluoro-phen-yl)-5-iodo-3-methyl-sulfinyl-1-benzofuran.2-（4-氟苯基）-5-碘-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 4;66(Pt 1):o44. doi: 10.1107/S1600536809051642.
2
5-Fluoro-2-(4-iodo-phen-yl)-3-methyl-sulfinyl-1-benzofuran.5-氟-2-(4-碘苯基)-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 8;65(Pt 9):o2115. doi: 10.1107/S1600536809030992.
3
2-(4-Iodo-phen-yl)-5,7-dimethyl-3-methyl-sulfinyl-1-benzofuran.2-（4-碘苯基）-5,7-二甲基-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2008 May 17;64(Pt 6):o1088. doi: 10.1107/S1600536808014104.
4
5-Bromo-2-(4-fluoro-phen-yl)-3-methyl-sulfinyl-1-benzofuran.5-溴-2-(4-氟苯基)-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 12;66(Pt 1):o104. doi: 10.1107/S1600536809052519.
5
5-Chloro-2-(4-fluoro-phen-yl)-3-methyl-sulfinyl-1-benzofuran.5-氯-2-（4-氟苯基）-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 3;65(Pt 11):o2649. doi: 10.1107/S1600536809039749.
6
3-(4-Fluoro-phenyl-sulfin-yl)-5-iodo-2-methyl-1-benzofuran.3-（4-氟-苯基亚磺酰基）-5-碘-2-甲基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 30;66(Pt 7):o1876. doi: 10.1107/S1600536810024931.
7
2-(4-Iodo-phen-yl)-5-methyl-3-methyl-sulfinyl-1-benzofuran.2-（4-碘苯基）-5-甲基-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2008 May 10;64(Pt 6):o1061. doi: 10.1107/S1600536808013706.
8
2-(4-Chloro-phen-yl)-5-fluoro-3-methyl-sulfinyl-1-benzofuran.2-（4-氯苯基）-5-氟-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 16;66(Pt 2):o364. doi: 10.1107/S1600536810001157.
9
5-Bromo-2-(4-fluoro-phen-yl)-7-methyl-3-methyl-sulfinyl-1-benzofuran.5-溴-2-(4-氟苯基)-7-甲基-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 19;66(Pt 1):o215. doi: 10.1107/S160053680905418X.
10
2-(4-Fluoro-phen-yl)-5-iodo-7-methyl-3-methyl-sulfinyl-1-benzofuran.2-（4-氟苯基）-5-碘-7-甲基-3-甲亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 16;66(Pt 7):o1680. doi: 10.1107/S1600536810022397.

引用本文的文献

1
2-(4-Fluoro-phen-yl)-5-iodo-3-isopropyl-sulfinyl-1-benzofuran.2-（4-氟苯基）-5-碘-3-异丙基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 20;66(Pt 12):o3261. doi: 10.1107/S1600536810047665.
2
5-Chloro-2-(4-chloro-phen-yl)-7-methyl-3-methyl-sulfinyl-1-benzofuran.5-氯-2-（4-氯苯基）-7-甲基-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2010 Feb 27;66(Pt 3):o706. doi: 10.1107/S1600536810006823.
3
5-Chloro-3-ethyl-sulfinyl-2-(4-fluoro-phen-yl)-1-benzofuran.5-氯-3-乙基亚磺酰基-2-(4-氟苯基)-1-苯并呋喃

本文引用的文献

1
5-Chloro-2-(4-fluoro-phen-yl)-3-methyl-sulfinyl-1-benzofuran.5-氯-2-（4-氟苯基）-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 3;65(Pt 11):o2649. doi: 10.1107/S1600536809039749.
2
5-Fluoro-2-(4-fluoro-phen-yl)-3-methyl-sulfinyl-1-benzofuran.5-氟-2-(4-氟苯基)-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 3;65(Pt 11):o2608. doi: 10.1107/S1600536809039312.
3
Synthesis of potent antitumor and antiviral benzofuran derivatives.强效抗肿瘤和抗病毒苯并呋喃衍生物的合成。
Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 20;66(Pt 2):o402. doi: 10.1107/S1600536810001728.
4
5-Bromo-3-ethyl-sulfinyl-2-(4-fluoro-phenyl)-1-benzofuran.5-溴-3-乙基亚磺酰基-2-(4-氟苯基)-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 9;66(Pt 2):o323. doi: 10.1107/S1600536810000590.
5
5-Cyclo-hexyl-2-(4-fluoro-phen-yl)-3-methyl-sulfinyl-1-benzofuran.5-环己基-2-（4-氟苯基）-3-甲基亚磺酰基-1-苯并呋喃
Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 22;67(Pt 2):o470. doi: 10.1107/S1600536811002297.
Bioorg Med Chem Lett. 2009 May 1;19(9):2420-8. doi: 10.1016/j.bmcl.2009.03.069. Epub 2009 Mar 21.
4
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
5
An overview of halogen bonding.卤素键概述。
J Mol Model. 2007 Feb;13(2):305-11. doi: 10.1007/s00894-006-0154-7. Epub 2006 Sep 30.
6
Artoindonesianins X and Y, two isoprenylated 2-arylbenzofurans, from Artocarpus fretessi (Moraceae).从桑科植物菲律宾波罗蜜（Artocarpus fretessi）中提取的两种异戊二烯化的2-芳基苯并呋喃类化合物，即印度尼西亚波罗蜜素X和Y。
Phytochemistry. 2003 Oct;64(4):831-4. doi: 10.1016/j.phytochem.2003.08.009.
7
Benzofurans and another constituent from seeds of Styrax officinalis.苯并呋喃及来自药用安息香种子的另一种成分。
Phytochemistry. 2003 Aug;63(8):939-43. doi: 10.1016/s0031-9422(03)00357-1.