Yoshikawa N, Ito H, Nakamura N
Department of Pediatrics, Kobe University Hospital, Japan.
Pediatrie. 1990;45(1):5-11.
Hereditary nephritis is usually accompanied by hematuria in childhood and, when associated with neurosensory deafness, is known as Alport's syndrome. In recent years, we have begun to understand that there are primary defects in glomerular basement membrane structure in hereditary nephritis. Increased knowledge concerning clinical and pathologic features has led to the identification of 4 types of hereditary nephritis. Herein, we review and update basic and clinical aspects of hereditary nephritis.
遗传性肾炎通常在儿童期伴有血尿，若伴有神经感觉性耳聋，则称为阿尔波特综合征。近年来，我们开始认识到遗传性肾炎存在肾小球基底膜结构的原发性缺陷。对临床和病理特征认识的增加，已导致识别出4种类型的遗传性肾炎。在此，我们对遗传性肾炎的基础和临床方面进行综述与更新。
