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异艾氏内酯的绝对构型

Absolute configuration of isoeichlerialactone.

作者信息

Fun Hoong-Kun, Joycharat Nantiya, Voravuthikunchai Supayang Piyawan, Chantrapromma Suchada

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 20;66(Pt 4):o879-80. doi: 10.1107/S1600536810009499.

DOI:10.1107/S1600536810009499
PMID:21580698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2984085/
Abstract

The title seco-dammarane triterpenoid, C(27)H(42)O(4) (systematic name: 3-{(3S,3aR,5aR,6S,7S,9aR,9bR)-6,9a,9b-trimethyl-3-[(R)-2-methyl-5-oxotetra-hydro-furan-2-yl]-7-(prop-1-en-2-yl)dodeca-hydro-1H-cyclo-penta-[a]naphthalen-6-yl}propanoic acid), has been isolated for the first time from the seeds of Aglaia forbesii. The mol-ecule has three fused rings and all rings are in trans-fused. The two cyclo-hexane rings are in standard chair conformations and the cyclo-pentane ring adopts an envelope conformation. Its absolute configuration was determined by the refinement of the Flack parameter to 0.26 (17). In the crystal, mol-ecules are linked into chains along [010] by O-H⋯O hydrogen bonds.

摘要

标题化合物裂环达玛烷三萜，化学式为C(27)H(42)O(4)（系统命名：3 - {(3S,3aR,5aR,6S,7S,9aR,9bR)-6,9a,9b - 三甲基 - 3 - [(R)-2 - 甲基 - 5 - 氧代四氢呋喃 - 2 - 基]-7 - (丙 - 1 - 烯 - 2 - 基)十二氢 - 1H - 环戊[a]萘 - 6 - 基}丙酸），首次从福氏米仔兰种子中分离得到。该分子有三个稠合环，且所有环均为反式稠合。两个环己烷环呈标准椅式构象，环戊烷环呈信封式构象。其绝对构型通过将Flack参数精修至0.26 (17)确定。在晶体中，分子通过O - H⋯O氢键沿[010]方向连接成链。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec8/2984085/037bd7a1381d/e-66-0o879-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec8/2984085/fae68351969a/e-66-0o879-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec8/2984085/037bd7a1381d/e-66-0o879-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec8/2984085/fae68351969a/e-66-0o879-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec8/2984085/037bd7a1381d/e-66-0o879-fig2.jpg

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Rocaglamide derivatives are immunosuppressive phytochemicals that target NF-AT activity in T cells.罗卡酰胺衍生物是一类免疫抑制性植物化学物质，可靶向作用于T细胞中的NF-AT活性。
J Immunol. 2005 Jun 1;174(11):7075-84. doi: 10.4049/jimmunol.174.11.7075.
6
Stress induced carbazole phytoalexins in Glycosmis species.
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