A rapid and simple method for introducing specific mutations into any position of DNA leaving all other positions unaltered.
作者信息
Tomic M, Sunjevaric I, Savtchenko E S, Blumenberg M
机构信息
Department of Dermatology, N.Y.U. Medical Center, NY 10016.
出版信息
Nucleic Acids Res. 1990 Mar 25;18(6):1656. doi: 10.1093/nar/18.6.1656.
Abstract
摘要
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本文引用的文献
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Fine structure genetic analysis of a beta-globin promoter.β-珠蛋白启动子的精细结构遗传分析
Science. 1986 May 2;232(4750):613-8. doi: 10.1126/science.3457470.
2
Construction of mutant and chimeric genes using the polymerase chain reaction.利用聚合酶链反应构建突变基因和嵌合基因。
Nucleic Acids Res. 1989 Jan 25;17(2):723-33. doi: 10.1093/nar/17.2.723.
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