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5-Acetyl-4-(2-chloro-phen-yl)-6-methyl-3,4-dihydro-pyrimidin-2(1H)-one.

作者信息

Anuradha N, Thiruvalluvar A, Pandiarajan K, Chitra S, Butcher R J

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 29;64(Pt 12):o2474-5. doi: 10.1107/S1600536808039366.

DOI:10.1107/S1600536808039366
PMID:21581440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2960013/
Abstract

In the title mol-ecule, C(13)H(13)ClN(2)O(2), the heterocyclic ring adopts a flattened boat conformation with the plane through the four coplanar atoms making a dihedral angle of 89.16 (5)° with the benzene ring, which adopts an axial orientation. The carbonyl, acetyl and methyl groups each have an equatorial orientation. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds lead to a tape motif. The H atoms of the methyl group at position 6 are disordered over two positions of opposite orientation.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb62/2960013/402dcc31c8d4/e-64-o2474-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb62/2960013/a13af973d193/e-64-o2474-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb62/2960013/402dcc31c8d4/e-64-o2474-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb62/2960013/a13af973d193/e-64-o2474-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb62/2960013/402dcc31c8d4/e-64-o2474-fig2.jpg

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引用本文的文献

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A short history of SHELX.SHELX简史。
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Synthesis and studies on some new fluorine containing triazolothiadiazines as possible antibacterial, antifungal and anticancer agents.一些新型含氟三唑并噻二嗪作为潜在抗菌、抗真菌和抗癌药物的合成与研究。
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