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(3S,7aR)-7-甲氧基-7a-甲基-3-苯基-2,3-二氢-吡咯并[2,1-b]恶唑-5(7aH)-酮

(3S,7aR)-7-Meth-oxy-7a-methyl-3-phenyl-2,3-dihydro-pyrrolo[2,1-b]oxazol-5(7aH)-one.

作者信息

Zheng Jian-Feng, Jiang Li-Jiao, Ye Jian-Liang

机构信息

The Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian 361005, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 6;65(Pt 1):o27. doi: 10.1107/S1600536808040105.

DOI:10.1107/S1600536808040105
PMID:21581670
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2967946/
Abstract

In the title chiral butterfly-like bicyclic lactam, C(14)H(15)NO(3), the phenyl and methyl groups are syn with respect to each other. The dihydro-pyrrrole ring adopts a boat conformation, whereas the oxazole ring has a slightly distorted boat conformation. The packing of mol-ecules in the crystal structure is stabilized by inter-molecular C-H⋯O hydrogen bonds.

摘要

在手性蝴蝶状双环内酰胺C(14)H(15)NO(3)的标题中，苯基和甲基彼此为顺式。二氢吡咯环呈船式构象，而恶唑环具有轻微扭曲的船式构象。晶体结构中分子的堆积通过分子间C—H⋯O氢键得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/386f/2967946/05955d580cee/e-65-00o27-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/386f/2967946/1bf3ead7bf86/e-65-00o27-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/386f/2967946/05955d580cee/e-65-00o27-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/386f/2967946/1bf3ead7bf86/e-65-00o27-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/386f/2967946/05955d580cee/e-65-00o27-fig2.jpg

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