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3-氨基-4H-噻吩并[2,3-b]吡啶-2-羧酸乙酯

Ethyl 3-amino-4H-thieno[2,3-b]pyridine-2-carboxyl-ate.

作者信息

Zheng Ren-Lin, Zhang Wen-Qin, Yu Luo-Ting, Yang Sheng-Yong, Yang Li

机构信息

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 3;65(Pt 1):o9. doi: 10.1107/S1600536808039974.

DOI:10.1107/S1600536808039974
PMID:21581727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2967861/
Abstract

The mol-ecule of the title compound, C(10)H(10)N(2)O(2)S, is essentially planar, except for the ethyl group, which is twisted away from the carboxyl plane by -90.5 (3)°. In the crystal structure, mol-ecules are linked into a zigzag sheet propagating along the b axis by inter-molecular N-H⋯O and N-H⋯N hydrogen bonds.

摘要

标题化合物C(10)H(10)N(2)O(2)S的分子基本呈平面状，除了乙基，它与羧基平面扭转了-90.5 (3)°。在晶体结构中，分子通过分子间的N-H⋯O和N-H⋯N氢键连接成沿b轴延伸的锯齿状片层。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/049c/2967861/54ec610a03c6/e-65-000o9-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/049c/2967861/1fd8c3386df8/e-65-000o9-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/049c/2967861/54ec610a03c6/e-65-000o9-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/049c/2967861/1fd8c3386df8/e-65-000o9-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/049c/2967861/54ec610a03c6/e-65-000o9-fig2.jpg

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