Tamada K, Kasai H, Hara M, Aoyama T, Takeuchi Y, Yamashita R
Department of Pediatrics, Keio University Ise Keio Hospital, Japan.
Acta Paediatr Jpn. 1990 Feb;32(1):98-103. doi: 10.1111/j.1442-200x.1990.tb00791.x.
A 7-month-old Japanese boy was diagnosed as having meningo-encephalitis with anterior horn cell damage. The complement fixation (CF) and hemagglutination inhibition (HI) tests showed increased antibody titers against Japanese encephalitis (JE) virus, but HI antibody in the mother's serum was not increased. It appears that the lack of JE-antibodies from the mother may have resulted in increased JE viral infectivity in the patient. A decrease in the incidence of antibodies against various viruses in women of childbearing age may lead to increased rates of severe viral infection in infants.
一名7个月大的日本男童被诊断为患有伴有前角细胞损伤的脑膜脑炎。补体结合（CF）试验和血凝抑制（HI）试验显示，其针对日本脑炎（JE）病毒的抗体滴度升高，但母亲血清中的HI抗体并未升高。母亲缺乏JE抗体可能导致了患儿感染JE病毒的几率增加。育龄女性针对各种病毒的抗体发生率降低，可能会导致婴儿严重病毒感染率上升。
