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2,6-二甲基-4-苯基-1,4-二氢吡啶-3,5-二羧酸二乙酯

Diethyl 2,6-dimethyl-4-phenyl-1,4-dihydro-pyridine-3,5-dicarboxyl-ate.

作者信息

Bai Ming-Sheng, Chen Yan-Yun, Niu Dong-Ling, Peng Li

机构信息

College of Life Science, Ningxia University, Yinchuan 750021, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 19;65(Pt 4):o799. doi: 10.1107/S1600536809009118.

DOI:10.1107/S1600536809009118
PMID:21582523
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2969073/
Abstract

The title mol-ecule, C(19)H(23)NO(4), was synthesized by the reaction of benzaldehyde, ethyl acetoacetate and NH(4)HCO(3). The dihydro-pyridine ring adopts a flattened boat conformation and the plane of the base of the boat forms a dihedral angle of 88.78 (9)° with the phenyl ring. The packing is stabilized by strong inter-molecular N-H⋯O and weak inter-molecular C-H⋯O hydrogen bonds.

摘要

标题分子C(19)H(23)NO(4)是通过苯甲醛、乙酰乙酸乙酯和NH(4)HCO(3)的反应合成的。二氢吡啶环呈扁平船式构象，船底平面与苯环形成88.78 (9)°的二面角。堆积通过强分子间N-H⋯O和弱分子间C-H⋯O氢键得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c3/2969073/a979ad9e7455/e-65-0o799-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c3/2969073/a979ad9e7455/e-65-0o799-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72c3/2969073/a979ad9e7455/e-65-0o799-fig1.jpg

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