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4-(1-甲基-1H-吡唑-5-基)哌啶-1-羧酸叔丁酯

tert-Butyl 4-(1-methyl-1H-pyrazol-5-yl)piperidine-1-carboxyl-ate.

作者信息

Richter Daniel, Kath John C, Rheingold Arnold L, Dipasquale Antonio, Yanovsky Alex

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 25;65(Pt 4):o870. doi: 10.1107/S1600536809010332.

Abstract

The reaction of (E)-tert-butyl 4-[3-(dimethyl-amino)acrylo-yl]piperidine-1-carboxyl-ate with methyl-hydrazine leads to the formation of the title compound, C(14)H(23)N(3)O(2), with a 1-methyl-1H-pyrazol-5-yl substituent. The plane of the pyrazole ring forms a dihedral angle of 33.4 (1)° with the approximate mirror plane of the piperidine ring.

摘要

(E)-4-[3-(二甲氨基)丙烯酰基]哌啶-1-羧酸叔丁酯与甲基肼反应生成标题化合物C(14)H(23)N(3)O(2),带有一个1-甲基-1H-吡唑-5-基取代基。吡唑环的平面与哌啶环的近似镜面形成33.4 (1)°的二面角。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f52d/2969088/3f439f6a1ab8/e-65-0o870-fig1.jpg

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