Yin Shaohong, Cui Yu, Xia Guangming, Zhang Yanju, Sun Guoxin
School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, People's Republic of China.
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 27;65(Pt 7):o1713. doi: 10.1107/S1600536809023721.
The title compound, C(27)H(27)N(3)O(6), a bis-amide derivative, is also a chiral amino acid ester with l-phenyl-alanine methyl ester groups as amine substituents. The pyridine ring is oriented at dihedral angles of 89.69 (3) and 62.95 (3)° with respect to the phenyl rings, while the dihedral angle between the phenyl rings is 60.76 (3)°. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into chains. One of the carbonyl O atoms and one of the meth-oxy CH(3) groups are disordered over two positions. The O atom was refined with occupancies of 0.69 (13) and 0.31 (13), while C and H atoms were refined with occupancies of 0.69 (8) and 0.31 (8).
标题化合物C(27)H(27)N(3)O(6)是一种双酰胺衍生物,也是一种手性氨基酸酯,其胺取代基为L-苯丙氨酸甲酯基团。吡啶环相对于苯环的二面角分别为89.69 (3)°和62.95 (3)°,而苯环之间的二面角为60.76 (3)°。在晶体结构中,分子间的N-H⋯O氢键将分子连接成链。其中一个羰基O原子和一个甲氧基CH(3)基团在两个位置上无序。O原子的占有率经精修为0.69 (13)和0.31 (13),而C和H原子的占有率经精修为0.69 (8)和0.31 (8)。