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（E）-2-[(2S,3S,12bR)-3-乙基-8-甲氧基-1,2,3,4,6,7,12,12b-八氢吲哚并[2,3-a]喹嗪-2-基]-3-甲氧基丙烯酸甲酯乙醇溶剂合物

(E)-Methyl 2-[(2S,3S,12bR)-3-ethyl-8-meth-oxy-1,2,3,4,6,7,12,12b-octa-hydro-indolo[2,3-a]quinolizin-2-yl]-3-methoxy-acrylate ethanol solvate.

作者信息

Carvalho Paulo, Furr Iii Edward B, McCurdy Christopher

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 May 29;65(Pt 6):o1441-2. doi: 10.1107/S1600536809017309.

DOI:10.1107/S1600536809017309
PMID:21583280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2969786/
Abstract

In the title compound, C(23)H(30)N(2)O(4)·C(2)H(6)O, the indole derivative has four fused rings, forming an indolo[2-3a]quinolizine system, in which one six-membered ring is directly connected to the indole unit and has a distorted chair conformation. The fourth ring is also a six-membered ring, depicting a regular chair conformation. In the crystal, the mol-ecules are linked by N-H⋯O and O-H⋯N inter-actions, forming a C(7) chain.

摘要

在标题化合物C₂₃H₃₀N₂O₄·C₂H₆O中，吲哚衍生物有四个稠合环，形成一个吲哚并[2-3a]喹嗪体系，其中一个六元环直接与吲哚单元相连且具有扭曲的椅式构象。第四个环也是一个六元环，呈现规则的椅式构象。在晶体中，分子通过N-H⋯O和O-H⋯N相互作用相连，形成一条C₇链。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef3/2969786/829ea2c41641/e-65-o1441-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef3/2969786/2dea53896779/e-65-o1441-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef3/2969786/829ea2c41641/e-65-o1441-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef3/2969786/2dea53896779/e-65-o1441-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ef3/2969786/829ea2c41641/e-65-o1441-fig2.jpg

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