Pham Phuong-Truc T
Department of Chemistry, Penn State Worthington Scranton, 120 Ridge View Drive, Dunmore, Pennsylvania 18512, USA.
Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 22;65(Pt 8):o1937. doi: 10.1107/S1600536809027743.
THE STRUCTURE OF ABACAVIR (SYSTEMATIC NAME: {(1S,4R)-4-[2-amino-6-(cyclo-propyl-amino)-9H-purin-9-yl]cyclo-pent-2-en-1-yl}methanol), C(14)H(18)N(6)O·2.5CH(3)OH, consists of hydrogen-bonded ribbons which are further held together by additional hydrogen bonds involving the hydroxyl group and two N atoms on an adjacent purine. The asymmetric unit also contains 2.5 mol-ecules of methanol solvate which were grossly disordered and were excluded using SQUEEZE subroutine in PLATON [Spek, (2009 ▶). Acta Cryst. D65, 148-155].
阿巴卡韦的结构（系统命名：{(1S,4R)-4-[2-氨基-6-(环丙基氨基)-9H-嘌呤-9-基]环戊-2-烯-1-基}甲醇），化学式为C(14)H(18)N(6)O·2.5CH(3)OH，由氢键连接的带状结构组成，这些带状结构通过涉及羟基和相邻嘌呤上两个氮原子的额外氢键进一步结合在一起。不对称单元还包含2.5个甲醇溶剂化物分子，这些分子严重无序，使用PLATON软件中的SQUEEZE子程序将其排除[Spek, (2009 ▶). Acta Cryst. D65, 148 - 155]。
