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（S）-6-{[（S）-2,2-二甲基-1,3-二氧戊环-4-基]甲基}-5,5-二氟-5,6-二氢-2H-吡喃-2-酮

(S)-6-{[(S)-2,2-Dimethyl-1,3-dioxolan-4-yl]meth-yl}-5,5-difluoro-5,6-dihydro-2H-pyran-2-one.

作者信息

Yin Zengsheng, Deng Xiangjun, Yao Rongxing, Li Hongqi, Zhao Pinqiao

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 25;65(Pt 8):o1967. doi: 10.1107/S1600536809028256.

DOI:10.1107/S1600536809028256
PMID:21583643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2977082/
Abstract

The title compound, C(11)H(14)F(2)O(4), is a γ,γ-gem-difluorinated α,β-unsaturated δ-lactone. The dioxolane five-membered ring and the lactone ring adopt half-chair conformations. There are two inter-molecular C-H⋯O inter-actions involving the carbonyl group as an acceptor which stabilize the crystal structure.

摘要

标题化合物C(11)H(14)F(2)O(4)是一种γ,γ-偕二氟取代的α,β-不饱和δ-内酯。二氧戊环五元环和内酯环呈半椅式构象。存在两种分子间C-H⋯O相互作用，其中羰基作为受体，这些相互作用稳定了晶体结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f340/2977082/60dbd8814102/e-65-o1967-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f340/2977082/35c21937d60e/e-65-o1967-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f340/2977082/b743540d9b7e/e-65-o1967-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f340/2977082/60dbd8814102/e-65-o1967-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f340/2977082/35c21937d60e/e-65-o1967-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f340/2977082/b743540d9b7e/e-65-o1967-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f340/2977082/60dbd8814102/e-65-o1967-fig3.jpg

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