儿童精神分裂症中氯氮平的应用。
Use of clozapine in childhood schizophrenia.
机构信息
T.N. SRINIVASAN, MD., Research Consultant, Schizophrenia Research Foundation, Anna Nagar East, Chennai 600 102.
出版信息
Indian J Psychiatry. 1997 Jul;39(3):262-4.
Childhood onset schizophrenia is a rare disorder whose prognosis is generally worse than that in the adult onset type of schizophrenia. Conventional neuroleptics have yielded inconsistent results with the risk of exposing the child to extrapyramidal and cognitive adverse effects which could interfere with proper development of the child. Effective and safe use of clozapine in children with schizophrenia has been reported. This drug is recently introduced in India and reports of its use in children are yet to come from this part of the world. This case report is on the effective and safe use of clozapine in a girl child with schizophrenia who became ill at 9 years of age.
儿童期发病精神分裂症是一种罕见疾病，其预后通常比成人发病精神分裂症差。传统的神经安定剂治疗效果不一致，且存在使儿童暴露于锥体外系和认知不良反应的风险，这可能会干扰儿童的正常发育。已有报道称氯氮平在儿童精神分裂症患者中的使用是有效且安全的。这种药物最近在印度推出，而来自世界这一地区的儿童使用氯氮平的报告尚不多见。本病例报告介绍了氯氮平在一名 9 岁起病的精神分裂症女童中的有效和安全使用。
Zotero 插件