Department of Surgery, New York University School of Medicine, New York, NY 10010, USA.
Surg Endosc. 2011 Sep;25(9):2844-8. doi: 10.1007/s00464-011-1629-x. Epub 2011 May 17.
Major thoracic or neck surgery or penetrating trauma can cause injury to the thoracic duct and development of a chylothorax. Chylothorax results in metabolic and immunologic disorders that can be life threatening, with a mortality rate reaching 50%. The management of chyle leaks is dependent on the etiology and daily output. Interventions are used to treat only leaks unresponsive to medical management or those with an output exceeding 1,000 ml/day.
This study reviewed the existing literature on the percutaneous management of chyle leaks. The authors evaluated five case series and three case reports inclusive of 90 patients in which percutaneous treatment for chylothorax was attempted between 1998 and 2004.
For 71 patients, percutaneous treatment was technically successful, and chylothorax resolved in 49 of the patients (69%). Percutaneous treatment of chylothorax was associated with a 2% morbidity rate and no mortality. For 19 patients whose percutaneous approach failed, either surgical ligation or pleurodesis was performed.
The percutaneous management of chyle leak is feasible, with low morbidity and mortality rates and a high rate of effectiveness. This approach should be considered before more invasive procedures.
大胸或颈部手术或穿透性创伤可导致胸导管损伤和乳糜胸的发展。乳糜胸会导致代谢和免疫紊乱,可能危及生命,死亡率高达 50%。乳糜漏的处理取决于病因和每日的输出量。干预措施仅用于治疗对药物治疗无反应或输出量超过 1000ml/天的漏液。
本研究回顾了关于乳糜漏经皮治疗的现有文献。作者评估了 1998 年至 2004 年间进行的五例系列病例和三例病例报告,其中共 90 例患者尝试了经皮治疗乳糜胸。
71 例患者的经皮治疗技术成功,49 例(69%)患者的乳糜胸得到缓解。乳糜胸经皮治疗的发病率为 2%,无死亡率。19 例经皮治疗失败的患者行手术结扎或胸膜固定术。
乳糜漏的经皮治疗是可行的,具有较低的发病率、死亡率和较高的有效性。在采用更具侵袭性的方法之前,应考虑这种方法。