Yoshioka Iwao, Tsujihata Masao, Okuyama Akihiko
Osaka University Graduate School of Medicine, Suita, Japan.
Arch Ital Urol Androl. 2011 Mar;83(1):26-30.
Sex hormones have substantial effects on crystal formation in the rat kidney through oxalate metabolism and oxidative cell damage. Testosterone is a promoter and estradiol an inhibitor of such crystal formation. The development of new medications related to sex hormones or GO are anticipated for sufferers of recurrent urolithiasis.