Soler Teresa, Lerin Angels, Serrano Teresa, Masferrer Emili, García-Tejedor Amparo, Condom Enric
Department of Pathology, Bellvitge University Hospital-ICS, L'Hospitalet de Llobregat, Barcelona, Spain.
Am J Dermatopathol. 2011 Jul;33(5):e54-7. doi: 10.1097/DAD.0b013e3181fd1eec.
Paget disease of the breast represents a cutaneous manifestation of an underlying breast malignancy. The rare finding of a pigmented Paget disease mimicking melanoma represents a diagnostic problem. We report a case of a pigmented lesion involving the breast nipple with an underlying infiltrating breast carcinoma, and we describe the clinical presentation, histological findings, and immunohistochemical features with a review of reported cases.
乳腺佩吉特病是一种潜在乳腺恶性肿瘤的皮肤表现。罕见的色素沉着性佩吉特病酷似黑色素瘤,这是一个诊断难题。我们报告一例累及乳腺乳头的色素沉着性病变伴潜在浸润性乳腺癌病例,并描述其临床表现、组织学特征和免疫组化特点,同时回顾已报道的病例。