Mosolov S N
Zh Nevropatol Psikhiatr Im S S Korsakova. 1990;90(1):80-7.
Based on clinico-catamnestic studies conducted in 50 patients with recurrent ("schizoaffective") schizophrenia 2 main types of an unfavourable disease course were distinguished: "stationary" (28 patients) and "labile-continual" (22 patients). The first variant was characterized by long and monotonous persistence of uniform affective delirious symptoms. The second variant was characterized by complete lack of any stability of the condition associated with permanent changing of polar affects and respective hallucinative delirious structures. Pronounced and reduced patterns of the disease course were distinguished in both variants. Clinical characteristics of the variants are provided, and ways by which they are formed are depicted. A number of theoretical problems, especially those concerned with the reliability of criteria for interrelations between the status and the disease course in the diagnosis and individual prognosis of the disease development are discussed.
基于对50例复发性(“分裂情感性”)精神分裂症患者进行的临床病史研究,区分出了两种主要的不良病程类型:“静止型”(28例患者)和“不稳定持续型”(22例患者)。第一种类型的特征是统一的情感性谵妄症状长期且单调地持续存在。第二种类型的特征是病情完全缺乏稳定性,伴有两极情感及相应的幻觉性谵妄结构的持续变化。在这两种类型中都区分出了明显和减轻的病程模式。文中给出了各类型的临床特征,并描述了它们的形成方式。还讨论了一些理论问题,尤其是那些与疾病状态和病程之间相互关系的标准在疾病发展诊断和个体预后中的可靠性相关的问题。