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4-氨基-N-(3-甲氧基吡嗪-2-基)苯磺酰胺

4-Amino-N-(3-meth-oxy-pyrazin-2-yl)benzene-sulfonamide.

作者信息

Bruni Bruno, Coran Silvia A, Bartolucci Gianluca, Di Vaira Massimo

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Sep 30;66(Pt 10):o2663. doi: 10.1107/S1600536810038158.

DOI:10.1107/S1600536810038158
PMID:21587634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2983257/
Abstract

The overall mol-ecular geometry of the title compound, C(11)H(12)N(4)O(3)S, is bent, with a dihedral angle of 89.24 (5)° between the best planes through the two aromatic rings. Each mol-ecule behaves as a hydrogen-bond donor toward three different mol-ecules, through its amidic and the two aminic H atoms, and it behaves as a hydrogen-bond acceptor from two other mol-ecules via one of its sulfonamidic O atoms. In the crystal, mol-ecules linked by N-H⋯N and N-H⋯O hydrogen bonds form kinked layers parallel to (001), adjacent layers being connected by van der Waals inter-actions.

摘要

标题化合物C(11)H(12)N(4)O(3)S的整体分子几何形状呈弯曲状，穿过两个芳香环的最佳平面之间的二面角为89.24 (5)°。每个分子通过其酰胺基和两个氨基H原子作为氢键供体与三个不同的分子相互作用，并通过其一个磺酰胺基O原子作为氢键受体接受另外两个分子的作用。在晶体中，通过N-H⋯N和N-H⋯O氢键连接的分子形成平行于(001)的扭结层，相邻层通过范德华相互作用相连。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/2983257/a5b937d3f23f/e-66-o2663-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/2983257/f89bc7206640/e-66-o2663-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/2983257/a5b937d3f23f/e-66-o2663-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/2983257/f89bc7206640/e-66-o2663-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/2983257/a5b937d3f23f/e-66-o2663-fig2.jpg

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