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5-甲氧基-1-(3,4,5-三甲氧基苯基)-1H-吲哚

5-Meth-oxy-1-(3,4,5-trimethoxy-phen-yl)-1H-indole.

作者信息

Monroe Thomas Blake, Rimland Casey, Moazami Yasamin, Jones Daniel S, Ogle Craig A

机构信息

Department of Chemistry, The University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte, NC 28223, USA.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 16;66(Pt 7):o1678. doi: 10.1107/S1600536810018568.

Abstract

The title compound, C(18)H(19)NO(4), was prepared as an indole derivative with possible anti-mitotic properties. The planes of the indole and trimethoxy-phenyl rings make a dihedral angle of 45.35 (5)° with one another. In the crystal, mol-ecules related by a twofold screw axis exhibit arene C-H⋯arene-π inter-actions which are 3.035 (1) Å in length.

摘要

标题化合物C(18)H(19)NO(4)被制备为一种具有潜在抗有丝分裂性质的吲哚衍生物。吲哚环和三甲氧基苯环的平面相互间形成45.35 (5)°的二面角。在晶体中,由二重螺旋轴相关的分子呈现出芳环C-H⋯芳环-π相互作用,其长度为3.035 (1) Å。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a892/3007039/dc48a7cfa423/e-66-o1678-fig1.jpg

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