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1,3,3-三甲基-1,2,3,4-四氢吡啶并[1,2-a]苯并咪唑-1-醇

1,3,3-Trimethyl-1,2,3,4-tetra-hydro-pyrido[1,2-a]benzimidazol-1-ol.

作者信息

Mehdi Sayed Hasan, Hashim Rokiah, Ghalib Raza Murad, Yeap Chin Sing, Fun Hoong-Kun

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 26;66(Pt 7):o1832. doi: 10.1107/S1600536810024487.

DOI:10.1107/S1600536810024487
PMID:21588036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3006987/
Abstract

In the title compound, C(14)H(18)N(2)O, the benzimidazole grouping is close to planar, with a maximum deviation of 0.042 Å; the six-membered non-aromatic ring adopts an envelope conformation. In the crystal structure, mol-ecules are linked into infinite sheets lying parallel to the bc plane by O-H⋯N and C-H⋯O hydrogen bonds.

摘要

在标题化合物C₁₄H₁₈N₂O中，苯并咪唑基团接近平面，最大偏差为0.042 Å；六元非芳香环呈信封构象。在晶体结构中，分子通过O—H⋯N和C—H⋯O氢键连接成平行于bc平面的无限片层。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30c/3006987/81a78e984a51/e-66-o1832-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30c/3006987/68dc94c449db/e-66-o1832-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30c/3006987/81a78e984a51/e-66-o1832-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30c/3006987/68dc94c449db/e-66-o1832-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d30c/3006987/81a78e984a51/e-66-o1832-fig2.jpg

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Bioorg Med Chem. 2008 Sep 15;16(18):8492-500. doi: 10.1016/j.bmc.2008.08.023. Epub 2008 Aug 12.
3
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Eur J Med Chem. 2008 Sep;43(9):1955-62. doi: 10.1016/j.ejmech.2007.12.005. Epub 2007 Dec 23.
4
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