17β-羟基-17α-（羟甲基）雌-4-烯-3-酮

Yousuf Sammer, Zafar Salman, Choudhary Muhammed Iqbal, Ng Seik Weng

Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 23;66(Pt 11):o2894. doi: 10.1107/S160053681004033X.

The title compound, C(19)H(28)O(3), the fungal-transformed metabolite of the steroid methyl-oestrenol contains four fused rings A, B, C and D. Ring A adopts a half-chair and the trans-fused rings B and C adopt chair confirmations; the five-membered D ring is folded like an envelope. In the crystal, adjacent mol-ecules are linked by O-H⋯O(carbon-yl) and O-H⋯O(hy-droxy) hydrogen bonds into a layer structure.

标题化合物C(19)H(28)O(3)，即甾体甲雌醇的真菌转化代谢产物，含有四个稠合环A、B、C和D。环A呈半椅式，反式稠合的环B和C呈椅式构象；五元D环像信封一样折叠。在晶体中，相邻分子通过O-H⋯O(羰基)和O-H⋯O(羟基)氢键连接成层状结构。