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1-乙酰基-2-r,6-c-双-(4-氯苯基)-3-甲基-1,2,5,6-四氢吡啶-4-基乙酸酯

1-Acetyl-2-r,6-c-bis-(4-chloro-phen-yl)-3-methyl-1,2,5,6-tetra-hydro-pyridin-4-yl acetate.

作者信息

Vimalraj V, Pandiarajan K

机构信息

Department of Chemistry, Annamalai University, Annamalai Nagar 608 002, Tamilnadu, India.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 20;66(Pt 12):o3259. doi: 10.1107/S1600536810047586.

DOI:10.1107/S1600536810047586
PMID:21589543
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3011578/
Abstract

In the title compound, C(22)H(21)Cl(2)NO(3), the pyridine ring adopts a half-chair conformation and the 4-chloro-phenyl groups occupy axial positions. The 4-chloro-phenyl groups are almost perpendicular to the plane of the tetra-hydro-pyridine ring forming dihedral angles 84.62 (6) and 85.55 (5)°; the dihedral angle between the two 4-chloro-phenyl rings is 12.16 (4)°. The crystal structure is stabilized by inter-molecular C-H⋯O inter-actions.

摘要

在标题化合物C(22)H(21)Cl(2)NO(3)中，吡啶环呈半椅式构象，4-氯苯基占据轴向位置。4-氯苯基几乎垂直于四氢吡啶环的平面，形成的二面角分别为84.62 (6)°和85.55 (5)°；两个4-氯苯环之间的二面角为12.16 (4)°。晶体结构通过分子间C-H⋯O相互作用得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd60/3011578/74cfe049e9b8/e-66-o3259-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd60/3011578/4bffe4768bf2/e-66-o3259-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd60/3011578/74cfe049e9b8/e-66-o3259-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd60/3011578/4bffe4768bf2/e-66-o3259-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd60/3011578/74cfe049e9b8/e-66-o3259-fig2.jpg

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本文引用的文献

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