Kim Jung-Keun, Lee Eunji, Lee Myongsoo
Center for Supramolecular Nanoassembly and Department of Chemistry, Seoul National University, Seoul 151-747, Korea.
Macromol Rapid Commun. 2010 Jun 2;31(11):980-5. doi: 10.1002/marc.200900879. Epub 2010 Mar 9.
A triblock amphiphilic macrocycle consisting of a macrocyclic aromatic segment, a hydrophilic oligo(ethylene oxide) branch, and a hydrophobic alkyl dendron is successfully synthesized and characterized. The resulting cyclic amphiphile is observed to self-assemble into hollow double-layered capsules in aqueous solution, as confirmed by dynamic light scattering and cryogenic transmission electron microscopy investigations. The capsules are able to encapsulate hydrophobic guest molecules through aromatic interactions with high stability.
一种由大环芳香族片段、亲水性聚环氧乙烷支链和疏水性烷基树枝状分子组成的三嵌段两亲性大环化合物成功合成并得到表征。通过动态光散射和低温透射电子显微镜研究证实，所得的环状两亲分子在水溶液中自组装成中空双层胶囊。这些胶囊能够通过芳香相互作用以高稳定性包封疏水性客体分子。
