Yang Jie, Gao Changyou
MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.
Macromol Rapid Commun. 2010 Jun 16;31(12):1065-70. doi: 10.1002/marc.200900901. Epub 2010 Apr 21.
Microcapsule arrays attract a lot of interest due to their potential applications in sensing technology. A strategy for fabricating diverse microcapsule arrays through covalent linking is reported here. The self-assembly of microcapsules was directed by using a poly(allylamine hydrochloride) (PAH)-patterned template, which was created via microcontact printing. The microcapsules with PAH as the outermost layer were treated with glutaraldehyde and then covalently immobilized on the PAH regions, resulting in ordered microcapsule arrays. The arrays had a high density of capsules and the aggregate number in a pattern could be well controlled by adjusting the area of the PAH pattern. A single microcapsule array could be obtained if the diameter of the PAH region was smaller than that of the microcapsules. These covalently assembled arrays could survive through successive incubation in solutions of high ionic strength and extreme pHs. Such good stability ensures further treatments, such as chemical reactions and loading of functional substances.
微胶囊阵列因其在传感技术中的潜在应用而备受关注。本文报道了一种通过共价连接制备多种微胶囊阵列的策略。微胶囊的自组装是通过使用聚（烯丙胺盐酸盐）（PAH）图案化模板来引导的，该模板是通过微接触印刷创建的。以PAH为最外层的微胶囊用戊二醛处理，然后共价固定在PAH区域上，从而形成有序的微胶囊阵列。这些阵列具有高密度的胶囊，并且通过调整PAH图案的面积可以很好地控制图案中的聚集数量。如果PAH区域的直径小于微胶囊的直径，则可以获得单个微胶囊阵列。这些共价组装的阵列可以在高离子强度和极端pH值的溶液中连续孵育后存活。这种良好的稳定性确保了进一步的处理，如化学反应和功能物质的负载。
