Guo Xuhong, Wang Jie, Li Li, Pham Duc-Truc, Clements Philip, Lincoln Stephen F, May Bruce L, Chen Qingchuan, Zheng Li, Prud'homme Robert K
State Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, PR China.
Macromol Rapid Commun. 2010 Feb 2;31(3):300-4. doi: 10.1002/marc.200900560. Epub 2009 Nov 24.
A close correllation between molecular-level interactions and macroscopic characteristics of polymer networks exists. The characteristics of the polymeric hydrogels assembled from β-cyclodextrin (β-CD) and adamantyl (AD) substituted poly(acrylate)s can be tailored through selective host-guest complexation between β-CD and AD substituents and their tethers. Dominantly, steric effects and competitive intra- and intermolecular host-guest complexation are found to control poly(acrylate) isomeric inter-strand linkage in polymer network formation. This understanding of the factors involved in polymeric hydrogel formation points the way towards the construction of increasingly sophisticated biocompatible materials.
聚合物网络的分子水平相互作用与宏观特性之间存在密切关联。由β-环糊精（β-CD）和金刚烷基（AD）取代的聚丙烯酸酯组装而成的聚合物水凝胶的特性，可以通过β-CD与AD取代基及其连接基团之间的选择性主客体络合来定制。主要发现，空间效应以及分子内和分子间主客体络合的竞争在聚合物网络形成过程中控制着聚丙烯酸酯异构体的链间连接。对聚合物水凝胶形成所涉及因素的这种理解为构建日益复杂的生物相容性材料指明了方向。
