Ohata Yoshihiro, Nakano Tsuyoshi, Maeda Yukiko, Kubo Kozo, Otsuka Noriyuki, Okamoto Kenzo
Department of Respiratory Medicine, Tomakomai City Hospital.
Nihon Kokyuki Gakkai Zasshi. 2011 Apr;49(4):277-81.
A 50-year-old man with a history of asbestos inhalation developed symptoms related to a metastatic brain tumor was admitted. Chest X-ray images showed an opacity in the left lower lung field. We were unable to differentiate between lung cancer and malignant pleural tumor using either transbronchial lung biopsy or computed tomography (CT)-guided needle biopsy. After 3 months the patient died from rapid disease progression despite radiation therapy, drainage of large quantities of the pleural effusion and chemotherapy. A diagnosis of asbestos-related pleomorphic carcinoma of the lung was made after autopsy and immunohistochemical examination of the tumor.
一名有石棉吸入史的50岁男性因出现与转移性脑肿瘤相关的症状而入院。胸部X光片显示左下肺野有一处不透明区。我们通过经支气管肺活检或计算机断层扫描(CT)引导下的针吸活检均无法区分肺癌和恶性胸膜肿瘤。3个月后,尽管进行了放射治疗、大量胸腔积液引流和化疗,患者仍因疾病快速进展而死亡。尸检及对肿瘤进行免疫组化检查后,诊断为石棉相关的肺多形性癌。