Institute of Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
N Engl J Med. 2011 May 19;364(20):1943-54. doi: 10.1056/NEJMra1011874.
In 2009, the United Nations Estimated that 33.2 Million People worldwide were living with human immunodeficiency virus type 1 (HIV-1) infection and that 2.6 million people had been newly infected. The need for effective HIV-1 prevention has never been greater. In this review, we address recent critical advances in our understanding of HIV-1 transmission and acute HIV-1 infection. Fourth-generation HIV-1 testing, now available worldwide, will allow the diagnosis of infection in many patients and may lead to new treatments and opportunities for prevention.
2009 年，联合国估计全球有 3320 万人感染了人类免疫缺陷病毒 1 型（HIV-1），并有 260 万人新感染。HIV-1 预防的有效性从未像现在这样重要。在这篇综述中，我们探讨了最近在 HIV-1 传播和急性 HIV-1 感染方面的理解的重要进展。目前全球范围内都可使用的第四代 HIV-1 检测将使许多患者能够诊断出感染，并可能带来新的治疗和预防机会。
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