Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
J Pediatr. 2011 Oct;159(4):571-6. doi: 10.1016/j.jpeds.2011.03.053. Epub 2011 May 17.
To examine race/ethnicity and neighborhood income differences in longitudinal patterns of deterioration in hemoglobin A1c (HbA1c) values among youth (age 10 to 18 years) with type 1 diabetes.
A sample of 225 youth (50.2% female), including 81 White, 81 Black, and 63 Hispanic youth with type 1 diabetes, was matched initially on age and sex. Neighborhood median family income was obtained through public census databases. Self-identified race/ethnicity and all HbA1c values (grand mean, 9.09% ± 2.02%) available in patients' medical records between age 10 and 18 years were recorded and analyzed.
Hierarchical linear modeling revealed age-related deterioration in HbA1c values that differed by race/ethnicity and income. Controlling for income, White and Hispanic youth had similar HbA1c values at the start of adolescence (age 10) and demonstrated similar rates of deterioration across adolescence. Blacks had higher initial HbA1c values compared with Whites and Hispanics, but a similar rate of deterioration. Higher neighborhood income was associated with slower deterioration in HbA1c value among White teens, but not among Hispanic or Black teens.
Longitudinally, Black youth appear to experience disproportionate risks compared with White and Hispanic youth when income is statistically controlled. Neither Black nor Hispanic youth appear to benefit from living in higher-income neighborhoods.
研究种族/族裔和邻里收入差异对青少年(10 至 18 岁)1 型糖尿病患者血红蛋白 A1c(HbA1c)值纵向恶化模式的影响。
本研究纳入了 225 名青少年(女性占 50.2%),包括 81 名白人、81 名黑人、63 名西班牙裔青少年,他们在年龄和性别上与患者相匹配。邻里中位数家庭收入通过公共人口普查数据库获得。记录并分析了患者病历中 10 至 18 岁之间自我识别的种族/族裔和所有 HbA1c 值(平均 9.09%±2.02%)。
分层线性模型显示,HbA1c 值随年龄的变化因种族/族裔和收入而异。在控制收入的情况下,白人青少年和西班牙裔青少年在青春期开始时 HbA1c 值相似,且在整个青春期都表现出相似的恶化率。与白人青少年和西班牙裔青少年相比,黑人青少年的初始 HbA1c 值更高,但恶化率相似。较高的邻里收入与白人青少年 HbA1c 值的恶化速度较慢有关,但与西班牙裔或黑人青少年无关。
纵向来看,与收入进行统计控制后,黑人青少年似乎比白人青少年和西班牙裔青少年面临更大的风险。黑人和西班牙裔青少年似乎都没有从居住在高收入社区中受益。