Wayne State University, Detroit, Michigan.
Pacific Northwest University of Health Sciences, Yakima, Washington.
Pediatrics. 2023 May 1;151(5). doi: 10.1542/peds.2022-058856.
Black youth with type 1 diabetes (T1D) are at heightened risk for suboptimal glycemic control. Studies of neighborhood effects on the health of youth with T1D are limited. The current study investigated the effects of racial residential segregation on the diabetes health of young Black adolescents with T1D.
A total of 148 participants were recruited from 7 pediatric diabetes clinics in 2 US cities. Racial residential segregation (RRS) was calculated at the census block group level based on US Census data. Diabetes management was measured via self-report questionnaire. Hemoglobin A1c (HbA1c) information was gathered from participants during home-based data collection. Hierarchical linear regression was used to test the effects of RRS while controlling for family income, youth age, insulin delivery method (insulin pump versus syringe therapy), and neighborhood adversity.
HbA1c was significantly associated with RRS in bivariate analyses, whereas youth-reported diabetes management was not. In hierarchical regression analyses, whereas family income, age, and insulin delivery method were all significantly associated with HbA1c in model 1, only RRS, age, and insulin delivery method were significantly associated with HbA1c in model 2. Model 2 explained 25% of the variance in HbA1c (P = .001).
RRS was associated with glycemic control in a sample of Black youth with T1D and accounted for variance in HbA1c even after controlling for adverse neighborhood conditions. Policies to reduce residential segregation, along with improved screening for neighborhood-level risk, hold the potential to improve the health of a vulnerable population of youth.
患有 1 型糖尿病(T1D)的黑人青年面临血糖控制不佳的风险增加。关于邻里效应对 T1D 青年健康影响的研究有限。本研究调查了种族居住隔离对年轻黑人青少年 T1D 患者糖尿病健康的影响。
从美国两个城市的 7 个儿科糖尿病诊所招募了总共 148 名参与者。根据美国人口普查数据,在人口普查街区组层面计算种族居住隔离(RRS)。通过自我报告问卷测量糖尿病管理。在家中收集数据时,从参与者那里收集血红蛋白 A1c(HbA1c)信息。使用分层线性回归来测试 RRS 的影响,同时控制家庭收入、青年年龄、胰岛素输送方法(胰岛素泵与注射器治疗)和邻里逆境。
在双变量分析中,HbA1c 与 RRS 显著相关,而青年报告的糖尿病管理则不然。在分层回归分析中,虽然家庭收入、年龄和胰岛素输送方法在模型 1 中均与 HbA1c 显著相关,但仅 RRS、年龄和胰岛素输送方法在模型 2 中与 HbA1c 显著相关。模型 2 解释了 HbA1c 变异的 25%(P =.001)。
在患有 T1D 的黑人青年样本中,RRS 与血糖控制相关,并且即使在控制了不利的邻里条件后,RRS 也解释了 HbA1c 的变异。减少居住隔离的政策,以及改善对邻里层面风险的筛查,有可能改善弱势群体青年的健康状况。