Clinical Infection Unit, St George's Hospital, Blackshaw Road, London SW17 0QT, UK.
J Infect. 2011 Jun;62(6):484-6. doi: 10.1016/j.jinf.2011.04.008. Epub 2011 Apr 27.
We present a rare case of chronic Pneumocystis jiroveci infection presenting as multiple persistent granulomatous pulmonary nodules over a 12 month period in a patient with follicular lymphoma undergoing treatment with Rituximab, Cyclophosphamide, Vincristine, and Prednisolone chemotherapy. Remarkably during this period the patient remained asymptomatic. This is the first case to combine these atypical histological, radiological, and clinical manifestations of P. jiroveci infection highlighting unusual manifestations of the disease.
我们报告了一例罕见的慢性肺孢子菌感染病例,该患者在接受利妥昔单抗、环磷酰胺、长春新碱和泼尼松化疗的滤泡性淋巴瘤治疗期间,12 个月内出现多个持续存在的肉芽肿性肺结节。在此期间,患者一直无症状,这一现象十分罕见。这是首例结合了肺孢子菌感染这种非典型组织学、影像学和临床表现的病例,突出了该疾病的不常见表现。